Dementia (SDAT)
别称：
Dementias
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Mental and Behavioural Disorders Due to Use of Sedatives or Hypnotics, Residual and Late-Onset Psychotic Disorder
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Primary Degenerative Alzheimer Type Dementia, Presenile Onset, Uncomplicated
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Dementia Due to Alzheimer Disease, Onset Unknown or Unspecified
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Dementia Due to Psychoactive Substances Including Medications
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Dementia Due to Other Specified Diseases Classified Elsewhere
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Late-Onset Psychoactive Substance-Induced Psychotic Disorder
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Residual and Late-Onset Alcohol-Induced Psychotic Disorder
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Dementia Due to Use of Sedatives, Hypnotics or Anxiolytics
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Primary Degenerative Alzheimer Type Dementia, Early Onset
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Primary Degenerative Alzheimer Type Dementia, Late Onset
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Dementia Due to Exposure to Heavy Metals or Other Toxins
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Dementia Due to Other Specified Psychoactive Substance
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Senile Primary Degenerative Alzheimer Type Dementia
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Dementia Due to Alzheimer Disease with Early Onset
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Early Onset Alzheimer Type Dementia, Uncomplicated
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Dementia Due to Alzheimer Disease with Late Onset
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Dementia in Alzheimer Disease with Early Onset
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Dementia in Alzheimer Disease with Late Onset
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Dementia Due to Diseases Classified Elsewhere
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Dementia Due to Normal Pressure Hydrocephalus
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Primary Degenerative Alzheimer Type Dementia
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Dementia Due to Human Immunodeficiency Virus
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Alzheimer Disease Dementia with Early Onset
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Alzheimer Disease Dementia with Late Onset
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Dementia Due to Use of Volatile Inhalants
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Dementia Due to Cerebrovascular Disease
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Dementia Syndrome of Parkinson Disease
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Hiv Associated Cognitive Motor Complex
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Senile Dementia of the Lewy Body Type
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Senile Dementia of the Alzheimer Type
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Dementia in Alzheimer Disease Type 2
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Dementia in Alzheimer Disease Type 1
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Late Onset Alzheimer Brain Sclerosis
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Presenile Alzheimer Brain Sclerosis
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Alzheimer's Type Atypical Dementia
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Dementia Due to Huntington Disease
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Dementia Due to Multiple Sclerosis
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Dementia Due to Injury to the Head
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Dementia Due to Alzheimer Disease
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Alzheimer Type Presenile Dementia
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Dementia Due to Lewy Body Disease
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Dementia Due to Parkinson Disease
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Dementia Due to Niacin Deficiency
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Senile Alzheimer Brain Sclerosis
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Chronic Alcoholic Brain Syndrome
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Hiv Associated Dementia Complex
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Dementia of the Lewy Body Type
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End Stage Alzheimer's Dementia
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Early Onset Alzheimer Dementia
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Senile Alzheimer Brain Disease
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Dementia Due to Use of Alcohol
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Late Onset Alcoholic Psychosis
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Late Onset Alzheimer Dementia
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Vascular Cognitive Impairment
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Dementia in Paralysis Agitans
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Dementia in Parkinson Disease
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Dementia in Huntington Chorea
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Dementia Due to Prion Disease
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Dementia Due to Down Syndrome
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Alzheimer Disease Dementia
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Strategic-Infarct Dementia
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Volatile Solvents Dementia
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Parkinson Related Dementia
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Dementia with Lewy Bodies
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Presenile Brain Sclerosis
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Arteriosclerotic Dementia
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Alcohol-Related Dementia
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Alcohol-Induced Dementia
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Alcoholic Brain Syndrome
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Dementia Due to Pellagra
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Alzheimer Type Dementia
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Alcoholic Dementia Nos
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Aids Dementia Complex
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Aids Related Dementia
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Post Stroke Dementia
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Alzheimer Sclerosis
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Presenile Sclerosis
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Alzheimer Dementia
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Presenile Dementia
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Vascular Dementia
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Inhalant Dementia
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Alcohol Dementia
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Hiv Dementia
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Sdat
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Sdlt
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Pdd
基础信息
疾病表征
基因 & 突变
靶点药物
疾病模型
文献报道
Dementia is a syndrome associated with neurodegenerative diseases, leading to a decline in cognitive abilities affecting daily activities. Symptoms include memory problems, emotional issues, and difficulties with language. It is not a normal part of aging and can range from mild to severe stages. Age is a primary risk factor, and it is not inevitable with aging. Mild cognitive impairment is a stage between normal aging and dementia. Dementia can have multiple causes, including Alzheimer's disease, vascular disease, Lewy body disease, substance use, and exposure to toxins. Genetic factors can play a role in Alzheimer's disease. Dementia can also be caused by head injury, nutritional deficiencies, Down syndrome, and other specific conditions. Symptoms vary depending on the cause, with cognitive deficits affecting memory, language, judgment, and behavior. Diagnosis requires observing a change from usual mental functioning and greater cognitive decline than normal aging.
相关ID：
基础信息
遗传方式 | 发病时间 | 患病率/发病率 | 相关基因 | 相关模型 | 参考文献 | MALACARDS |
|---|---|---|---|---|---|---|
Ot 其他 | 未知 | -- | 754 | 6429 | 3 |
疾病表征
当前疾病关联的表型信息：
分类：疾病表征所属解剖分类；
HPO概率/Orphanet概率：对应表征在当前疾病的发生概率，可根据发生概率进行排序；
HPO来源：跳转至HPO查看表征详情。
数据来源：HPO、Orphanet
基因 & 突变
当前疾病关联的基因及其突变：
作用分类：基因的主要生物学作用；
分值：疾病与基因之间的关联强度，分值越高，关联越紧密；
突变数量：疾病与基因相关的突变数量，括号内数字为同一Clinvar ID关联的数据总量，点击数字即可查看突变详情。
数据来源：Clinvar
靶点药物
与当前基因相关药物，展示CAS号、研发与临床试验状态。
数据来源：Clinical Trials
相关模型
当前基因相关的小鼠模型，点击模型名称，可查看模型详情。
数据来源：MGI
文献报道
当前基因最为密切相关的文献，可按年份、文献类型筛选，并可根据影响因子排序。
数据来源：Uniprot、PubMed