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Autism Spectrum Disorder (ASD)
别称:
Autism Spectrum Disorders
|
Autism Spectrum Disorder Without Disorder of Intellectual Development and with Mild or No Impairment of Functional Language
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Autism Spectrum Disorder with Disorder of Intellectual Development and with Mild or No Impairment of Functional Language
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Autism Spectrum Disorder Without Disorder of Intellectual Development and with Impaired Functional Language
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Autism Spectrum Disorder with Disorder of Intellectual Development and with Absence of Functional Language
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Autism Spectrum Disorder with Disorder of Intellectual Development and with Impaired Functional Language
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Pervasive Developmental Disorder, Not Otherwise Specified
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Other Specified Autism Spectrum Disorder
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Autism Spectrum Disorder, Unspecified
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Autistic Disorder of Childhood Onset
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Pervasive Developmental Delay Nos
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Pervasive Developmental Disorder
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Pervasive Development Disorder
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Autistic Continuum
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Autistic Disorder
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Autistic Behavior
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Childhood Autism
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Infantile Autism
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Kanner Syndrome
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Autistic
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Asd
基础信息
疾病表征
基因 & 突变
靶点药物
疾病模型
文献报道
Autism spectrum disorder (ASD) is a neurological and developmental condition that begins early in childhood and lasts throughout a person's life. It affects how a person acts, interacts with others, communicates, and learns. ASD is a spectrum disorder, meaning individuals can have a range of symptoms, including difficulties in social interactions, communication problems, and repetitive behaviors. The causes of ASD are not fully understood, but research suggests that both genes and the environment play important roles. Early intervention services can greatly improve the development of a child with ASD. Treatments for ASD include behavior and communication therapies, skills training, and medications to control symptoms. People with ASD may have a wide range of intellectual abilities and language skills, with some individuals having advanced conversation skills while others may be nonverbal. Symptoms of ASD can manifest as early as 1 to 2 years of age, with impaired social skills, communication problems, and repetitive actions being key characteristics. Individuals with ASD may have difficulties developing and maintaining friendships, communicating with peers and adults, and understanding expected behaviors in various settings. The disorder can cause impairment in personal, family, social, educational, occupational, or other important areas of functioning.
相关ID:
MALACARDS: ATS007
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MESH: D000067877
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ICD11: 120443468
基础信息
遗传方式
发病时间
患病率/发病率
相关基因
相关模型
参考文献
MALACARDS
Ot
其他
未知
--
5233
32187
31
ATS007
疾病表征
当前疾病关联的表型信息:
分类:疾病表征所属解剖分类;
HPO概率/Orphanet概率:对应表征在当前疾病的发生概率,可根据发生概率进行排序;
HPO来源:跳转至HPO查看表征详情。
数据来源:HPO、Orphanet
基因 & 突变
当前疾病关联的基因及其突变:
作用分类:基因的主要生物学作用;
分值:疾病与基因之间的关联强度,分值越高,关联越紧密;
突变数量:疾病与基因相关的突变数量,括号内数字为同一Clinvar ID关联的数据总量,点击数字即可查看突变详情。
数据来源:Clinvar
靶点药物
与当前基因相关药物,展示CAS号、研发与临床试验状态。
数据来源:Clinical Trials
相关模型
当前基因相关的小鼠模型,点击模型名称,可查看模型详情。
数据来源:MGI
文献报道
当前基因最为密切相关的文献,可按年份、文献类型筛选,并可根据影响因子排序。
数据来源:Uniprot、PubMed
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