Dementia, Frontotemporal, with or Without Parkinsonism
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Semantic Primary Progressive Aphasia
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Semantic Variant of Primary Progressive Aphasia
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Dementia, Frontotemporal
基础信息
疾病表征
基因 & 突变
靶点药物
疾病模型
文献报道
Semantic dementia is a form of frontotemporal dementia characterized by the progressive loss of semantic knowledge and behavioral abnormalities due to degeneration of the anterior temporal lobes. It is also known as semantic variant primary progressive aphasia and results in a loss of semantic memory in both verbal and non-verbal domains, with common symptoms being a loss of word meaning. Patients with this disorder may struggle to match words or images to their meanings, and while category-specific impairments are rare, a generalized semantic impairment typically occurs.