Hereditary pancreatitis is a rare genetic condition characterized by recurrent episodes of pancreas inflammation, leading to permanent damage and loss of function. Symptoms typically start in childhood and include abdominal pain, nausea, and vomiting. Chronic pancreatitis can develop, causing fatty stools, weight loss, and nutrient absorption issues. The condition is often caused by a faulty PRSS1 gene inherited in an autosomal dominant pattern. Complications may include an increased risk of type 1 diabetes and pancreatic cancer. Pancreatic fibrosis can impair enzyme production, leading to digestive problems. The risk of pancreatic cancer and diabetes increases with age. Death is commonly due to complications from pancreatic cancer or diabetes, but individuals with hereditary pancreatitis are believed to have a normal life expectancy.